Asymmetric semipinacol rearrangement of 2,3-allenols with N-bromo-1,8-naphthalimide.
نویسندگان
چکیده
A method using quinidine and optically active binol-derived phosphoric acid as a cocatalyst to catalyze the asymmetric semipinacol rearrangement of 2,3-allenols forming optically active 3-bromo-3-enals that contain an all-carbon quaternary stereocenter has been developed. After some further treatments, the products with practical enantiomeric purity could be prepared.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 34 شماره
صفحات -
تاریخ انتشار 2014